Vaccine Success. Let the good times return.

RandySavage said:
Good news doesn't promote website clicks or sell advertising slots on the TV
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of course it does, people see royal weddings as good news, and people buy the papers in droves at that time. A vaccine is a REAL bit of good news, I think papers are skeptical about pushing too hard that a vaccine exists, when the efficacy of the claim needs checking.
 
BoroMart said:
of course it does, people see royal weddings as good news, and people buy the papers in droves at that time. A vaccine is a REAL bit of good news, I think papers are skeptical about pushing too hard that a vaccine exists, when the efficacy of the claim needs checking.
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And how many royal weddings have you seen in your lifetime?
 
A bit more on the BBC this evening, regarding the Russian vaccine -

'Russia is pushing ahead with a coronavirus vaccine, working with manufacturers in Brazil and India to produce it in what it says is "very large amounts".
Kirill Dmitriyev, head of Russia's Direct Investment Fund, said it was expected to be registered in the next 10 days.
He said reports in the West that it may be unsafe were an example of "dishonest competition". Mass vaccine production in September is Russia's goal. They have more than one such vaccine in the pipeline.
But Dr Elisabetta Groppelli, a virologist and lecturer in global health at St George's, University of London, told BBC Radio 4's PM no data had yet been shared about the safety and efficacy of the vaccine.
"It's quite worrying that the claims have been made without showing data," she said.
The scientific community felt there has been an element of rushing - and the possibly of shortcuts having been taken - when it comes to a Russian vaccine, she added.'
 
FabioPorkpie said:
A bit more on the BBC this evening, regarding the Russian vaccine -

'Russia is pushing ahead with a coronavirus vaccine, working with manufacturers in Brazil and India to produce it in what it says is "very large amounts".
Kirill Dmitriyev, head of Russia's Direct Investment Fund, said it was expected to be registered in the next 10 days.
He said reports in the West that it may be unsafe were an example of "dishonest competition". Mass vaccine production in September is Russia's goal. They have more than one such vaccine in the pipeline.
But Dr Elisabetta Groppelli, a virologist and lecturer in global health at St George's, University of London, told BBC Radio 4's PM no data had yet been shared about the safety and efficacy of the vaccine.
"It's quite worrying that the claims have been made without showing data," she said.
The scientific community felt there has been an element of rushing - and the possibly of shortcuts having been taken - when it comes to a Russian vaccine, she added.'
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Bloomin Ruskis
 
Liamo said:
I might be more impressed if they had published the results of animal trials, plus phase 1, 2 & 3 randomized, double-blind placebo-controlled studies before declaring success.

If they have published such data, I'm not aware of it and a quick search doesn't turn up anything either. I'd also be concerned by the small number of participants - from the reports I've seen, the vaccine has been given to less than 100 people so far.

By contrast, reputable groups such as the Oxford team, have published full results of properly-conducted trials at each stage so far. In a couple of months (hopefully) results of their phase 3 trials should be available, by which time around 60,000 people will have taken their vaccine and we'll see where we are then.
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Don't take it then!
 
Gotta love all the bravado on here over taking a sparsely tested vaccine.
You should be treating any fast-tracked vaccine with caution, let alone one from Russia.
Let's see the data on it before making any rush to hail it as anything other than a promising development.
 
dooderooni said:
Gotta love all the bravado on here over taking a sparsely tested vaccine.
You should be treating any fast-tracked vaccine with caution, let alone one from Russia.
Let's see the data on it before making any rush to hail it as anything other than a promising development.
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You're right. Let's not dismiss it out of hand.
 
hopesoboro said:
Don't take it then!
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Until I've read the properly-published scientific evidence of the results they've obtained so far and they conduct phase 3 trials on tens of thousands of volunteers and publish those results, I most certainly won't.

Incidentally, this has nothing to do with where the vaccine comes from, it's purely the fact that they are not following established trial protocols and not publishing their results.

As The Guardian (hardly known for being reflexively anti-Russian) puts it:

While the mechanism for the Russian vaccine has been described, no data on its safety has been published ...
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https://www.theguardian.com/world/2...ad-of-rivals-in-race-to-produce-covid-vaccine
 
Liamo said:
I'm not in favour of dismissing anything out of hand. I would like to see them actually publish the safety data and conduct proper phase 3 trials however.
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agreed, it's simply a healthy skepticism until established protocols for safety have been followed.
 
I wonder what the economic value of mass vaccination would be if you get do it 6 months or 12 months earlier than everyone else- and also the impact on other nations not seen to be rushing one through.

Certainly once any country starts vaccinating you would imagine there would be a push to join them by other nations very quickly to stop them getting an upperhand. I haven't seen any info regarding China and vaccinations- are they ahead of the game or running due process?
 
Do we know how long the antibodies resulting from this vaccine will last in the body?

As far as I am aware people who have had this virus and have been asymptomatic or had very mild symptoms have either developed no antibodies or if they did they have only retained them for a short time.

This suggests the herd immunity strategy was doomed from the start. What is more, this is typical of coronaviruses.

If the vaccine does work, how often will we have to take boosters? Every year? Every 3 months? Side effects might be very important.
 
Lefty said:
Do we know how long the antibodies resulting from this vaccine will last in the body?

As far as I am aware people who have had this virus and have been asymptomatic or had very mild symptoms have either developed no antibodies or if they did they have only retained them for a short time.

This suggests the herd immunity strategy was doomed from the start. What is more, this is typical of coronaviruses.

If the vaccine does work, how often will we have to take boosters? Every year? Every 3 months? Side effects might be very important.
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There aren't any obvious answers for that. No one knows the level of antibodies that equate to immunity, or how long it'll last. Evidence of T-cells may be important but interestingly, those with asymptomatic positives have been found to be people with low natural immunity responses. Spanish Flu was strange in that the first wave hit the normal flu age range, but the second badly hit 18-35 year olds. Lots of theories as to why this was.

I see there is another drive today to collect blood plasma from recovered patients. This was tried extensively in the Spanish Flu epidemic as a last resort but little evidence it worked.

Lots of research seems to think a range of vaccine types may be necessary (mixed) to suit different demographics and how they respond to the virus.
 
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