Coronavirus good news thread

Liamo

Active member
As for [the] statement: "clearly there is other forms of immunity than anti body creation"..... please point me in the direction of those studies, would be great to see them.
Not 100% sure but I think this is a reference to the innate (as opposed to the adaptive) immune system. Antibodies are part of the adaptive immune system, that usually show up in the body around 1 - 2 weeks after exposure to a pathogen.

Prior to that, the innate immune system does what it can to fend off an infection. The innate immune system consists of, "physical and chemical barriers, phagocytic leukocytes, dendritic cells, natural killer cells, and plasma proteins."

This is explained in a number of different medical texts, here's just one example.

Difference between innate & adaptive immunity
 

RandySavage

Well-known member
These are interesting interviews, the problem with them is people take selected parts to quote and ignore all of the rest. They use it to push their viewpoint and ignore the balance within the interview. It is her belief that the epidemic is on its way out and she openly admits that it is impossible to prove this and impossible to show that there is the level of immunity within the population that she believes there is. I obviously hope she is correct.

Sadly if it chimes with ones view people will just rally behind it, trash Ferguson, and ignore the balance that she provides. She says that both hers and Fergusons (Neil, not Niall btw borolad259) models could have been consistent with the data in the early stages. It all depends on which assumptions fed into the models were correct. She obviously believes her model to be correct but admits it can't be proven. Her 1 in 10,000 IFR seems more than little suspect given around 35,000 deaths (conservative estimate).

Her discussion around other possible modes of immunity is interesting (as is Shane Crotty's study and Karol Sikora's views). That serological studies could put a 'lower bound' on the levels of spread within the population is also interesting.

She also acknowledges Ferguson's model was a worst case scenario and also a 'do nothing' scenario. There is simply no way to tell if it was correct as no country in the world, as far as I know, has done nothing. And a fair while before Johnson's message to avoid pubs and restaurants people already were. Public transport usage was already down, people were beginning to work from home, distancing in workplaces was being introduced.

It is also worth pointing out that Ferguson's model predicted ~approx 20,000 deaths with a suppression strategy and we are already above that. However, people just want to shout "he predicted 500,000 deaths and there has been no where near that!" ignoring the fact that was a "DO NOTHING" scenario which was obviously never going to happen in real life, its a mathematical model.

I have no particular reason to defend Ferguson and I hope he is/was wrong but I don't like his work simply being mis-represented.
I'm still waiting for Ferguson to apologize to the families of the farmers who killed themselves when his foot and mouth predictions were way off the mark and caused the deaths of many livestock and livelihoods.

👀

Anyways, good news? My tan is coming along nicely, doing a 7 mile walk today.
 

bear66

Well-known member
T-cells found to be very low in those severely affected so a new treatment is being trialled which aims to increase the T-cell count. This could be a significant treatment option going forward.

https://www.bbc.co.uk/news/health-52754280
That's an important finding it further validation takes place. Identifying those most at risk rather than broadbrush will allow focused prevention and treatment.
 

borolad259

Administrator
Staff member
That's an important finding it further validation takes place. Identifying those most at risk rather than broadbrush will allow focused prevention and treatment.
I think this is the future where this disease is concerned. Understanding why some people get so sick/die and finding ways to protect them. The T cell discovery ties in with the Vitamin D deficiency link with poor outcomes, as Vit D plays a crucial role in T cell production.
 
Karol Sikora has just tweeted this

Interesting to read Oxford vaccine project leader Prof Adrian Hill is feeling pessimistic about their vaccine.

He fears there simply won't be enough virus in the community for the volunteers to get infected in the trial.

The virus is on the wane.
 

bear66

Well-known member
Karol Sikora has just tweeted this

Interesting to read Oxford vaccine project leader Prof Adrian Hill is feeling pessimistic about their vaccine.

He fears there simply won't be enough virus in the community for the volunteers to get infected in the trial.

The virus is on the wane.
That was said to be a problem a month ago that the window of opportunity was likely to disappear. They should have organised testing trials in a country where the virus was just beginning to take hold.
 
That was said to be a problem a month ago that the window of opportunity was likely to disappear. They should have organised testing trials in a country where the virus was just beginning to take hold.
They were talking about doing the trials in other countries where the virus is more prevalent several months ago and said they were already setting up the arrangements for it to be done that way, if necessary.
 
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