35,000 excess cancer deaths

That's quite a personal question @bear66 what's your STI status 👀?

Oh I don't know, flu? Pneumonia? Had that when I was 5 years old, 3 night stay on the old Middlesbrough General. Probably had the flu before. Definitely had man flu, usually following excessive Xmas celebrations 😀
I've had it once. A very contagious annual virus. I've never attempted to social distance from flu carriers. I'd be surprised if more than 8% have had covid-19 in the UK and their antibodies are getting less by the day.
 
@Statto1 @Laughing , would it be fair to assume that the vast majority of the population have already had it?
Reason I ask this as it's becoming known the virus was starting to fly around Europe as far back as November last year. If the virus is as contagious as we are told it is (airborne, surviving for days on end on surfaces etc) you don't have to a scientist to come to the common sense conclusion it's been everywhere. Climate obviously plays a huge part in all of this too as seen by the cases falling when the weather was superb and rising again when it started getting colder, none of these inside outside ventilation excuses.

Thoughts?

First proven case was in Europe was 27th December in France. It was probably here before then but infections can't have been high as when you get high infections you get the associated rise in deaths. The first deaths of covid were probably not spotted and put down to pneumonia or flu. I don't think many people in this country have had it for 2 reasons. Firstly the antibody tests show less than 10% of the population have antibodies for covid and seconded we would have seen a lot more excess deaths before March.
 
First proven case was in Europe was 27th December in France. It was probably here before then but infections can't have been high as when you get high infections you get the associated rise in deaths. The first deaths of covid were probably not spotted and put down to pneumonia or flu. I don't think many people in this country have had it for 2 reasons. Firstly the antibody tests show less than 10% of the population have antibodies for covid and seconded we would have seen a lot more excess deaths before March.
Yeah it's an interesting debate that still hasn't been had, at least publicly. I imagine it's been discussed a lot behind closed doors around Europe and the rest of the world..
 
One thing I very much agree with T_A_D about is the antibody numbers being pretty meaningless. T-cell immune response probably takes care of the inflection in most folk, without getting the antibody level of defence. Additionally, antibodies don’t appear immediately OR stay around for too long, so any antibody test would need to be done in the correct, limited time window in order to pick them up. Plenty of people who have come back with no antibodies may have either not-yet produced them when tested or produced them and they’ve gone by the time they are tested, or never produced them because the killer t-cells did the biz before antibody last were needed.
It’s very difficult to say how many have been exposed to the virus but I do think it’s significantly higher than the stated numbers based on antibody studies.
 
One thing I very much agree with T_A_D about is the antibody numbers being pretty meaningless. T-cell immune response probably takes care of the inflection in most folk, without getting the antibody level of defence. Additionally, antibodies don’t appear immediately OR stay around for too long, so any antibody test would need to be done in the correct, limited time window in order to pick them up. Plenty of people who have come back with no antibodies may have either not-yet produced them when tested or produced them and they’ve gone by the time they are tested, or never produced them because the killer t-cells did the biz before antibody last were needed.
It’s very difficult to say how many have been exposed to the virus but I do think it’s significantly higher than the stated numbers based on antibody studies.
I put up a link to a paper the other day questioning whether either or both the two types of T-cells are good/bad. T-cells are found in severe hospital cases which puts a major question mark over their physiology.
 
I put up a link to a paper the other day questioning whether either or both the two types of T-cells are good/bad. T-cells are found in severe hospital cases which puts a major question mark over their physiology.

I missed that one - thanks for highlighting. Will have a look at it tomorrow 👍
 
I missed that one - thanks for highlighting. Will have a look at it tomorrow 👍

“Most, although not all, patients who are hospitalized seem to mount both CD8+ and CD4+ T cell responses, and evidence points to possible suboptimal, excessive or otherwise inappropriate T cell responses associated with severe disease.”


Link

And

“Even if our most optimistic speculations about cross-reactive T cell memory were found to be correct,” says Shane Crotty, an immunologist at the La Jolla Institute for Immunology, “the most likely effect would be not a prevention of SARS-CoV-2 infections. Instead, the cross-reactive T cell memory would reduce the disease severity, such that fewer people would become severely ill or die from COVID-19.”


Link
 
I put up a link to a paper the other day questioning whether either or both the two types of T-cells are good/bad. T-cells are found in severe hospital cases which puts a major question mark over their physiology.

There are other studies too, including from the Karolinksa institute. I also included a video from John Campbell which explains the papers.

But you want to stick to 8% immunity.

Lets apply some simple logic. If we only had 8% immunity deaths would raging all over the country. They simply aren't. As a percentage of daily deaths from all other forms it is tiny! It was huge in March, April. The North West / North is experiencing the last of it. London looks through. Sweden done.


Yet, we have a government who wants to introduce social controls in London without data to justify it. SAGE completely unaccountable, they can't justify 8% because it makes no sense at all. It would be a pretty weird virus if we only had antibody response! We'd be picking dead bodies out of the street if it was 8%!

Social controls and restrictions of freedoms are happening, drip by drip, lockdown to Christmas, lockdown to vaccine when completely pointless unless virus becomes endemic and a vaccine would help vulnerable but only after testing, which cannot be rushed.
 
@Statto1 @Laughing , would it be fair to assume that the vast majority of the population have already had it?
Reason I ask this as it's becoming known the virus was starting to fly around Europe as far back as November last year. If the virus is as contagious as we are told it is (airborne, surviving for days on end on surfaces etc) you don't have to a scientist to come to the common sense conclusion it's been everywhere. Climate obviously plays a huge part in all of this too as seen by the cases falling when the weather was superb and rising again when it started getting colder, none of these inside outside ventilation excuses.

Thoughts?

No, it wouldn't suggest the vast majority of the population have had it (which I'm taking you mean 66% plus?), for a few reasons:
1) Cases/ graphs/ deaths etc wouldn't grow so fast, the effective R rate would have reduced as there would have been less susceptible people to pass it on to.
2) This was proven by the antibody test on New York, after they came out of their nightmare. They had 10 times more cases than they thought, but it was still only 1 in 7 of the population, and it got bad there.
3) We've also done antibody tests and surveys, which bring out the same results.
4) It's pretty well known that 80% don't get symptoms, so if you can find out the 20% that have, and work that v the population it gives a rough number.

No, it wasn't the climate (not for 80% of it anyway), as if it were, we would have had a blip in March and then a decline in April and May, not exponential growth.
The growth and death numbers reversed once we locked down (after the known delay), and because human contact was down by 70% (proven by phone analytics), and that's even including for the fact that people were practically guaranteed to pass it on to who they live with, as it was impossible for everyone to isolate alone.
One or two may have had it in November in Europe (whether it does makes little difference), but I don't think they did, as if they had there would have been the exponential growth and an absolute nightmare over Christmas with thousands on ventilators and an obvious excess death peak, which obviously did not happen.
The transmission capability has been proven, and proven as a big problem, as it's been proven by the cases, deaths, growth and countries that have all successfully tracked and traced (not us).

The climate does play a part as does UV light, everyone of credibility agrees it does, but what plays a bigger part is 80% being asymptomatic, yet contagious for days without even knowing it. It's got a natural R of somewhere between 2-4 times that of flu, and 5-10 times more lethal than flu. It's a big problem in summer, it's a massive problem in winter.
 
Lets apply some simple logic. If we only had 8% immunity deaths would raging all over the country. They simply aren't. As a percentage of daily deaths from all other forms it is tiny! It was huge in March, April. The North West / North is experiencing the last of it. London looks through. Sweden done.

No, that's not logical, but it takes some thinking to realise why, which I'll explain.

If more people had it, or had immunity then there wouldn't be the growth in deaths and cases that we're looking at now. We've still got massive growth yet our mobility is still down 20% to what it was end of March. So we're less mobile now, but it's still spreading just as much. Mobility dropped by 70% for April, this didn't change the virus genetic code, it just decreased the number of social interactions.

So, by your thinking, if we already have immunity, then that must mean that it's either got a lot more lethal than we thought or the natural R, has got a lot higher than we thought? Which is it?

It can't be that way above, as lethality and the natural R have not changed, so the only way to describe how it still is spreading so fast, is because there is still loads of available people to spread to (I there is not enough immunity). We might have 7-15% immunity, but it's not enough, if it was then there wouldn't be any crazy growth. What would the growth be if we were at 100% mobility, with no masks, pubs open etc, it would be through the roof.

The people are really important to this, it's the obedient nations and rule followers that seem to be doing the best.
London isn't done, but they got a bit of a kicking last time, so might have bucked up their ideas.
Sweden is a strange one, but they have had a lot of deaths for their population size, and the place is massive. But what they do is irrelevant to here, as they have people that trust in the government and the public are nothing like the shower of $hit we have over here. I can't imagine they're getting many visitors from other countries and it's not exactly a goods or travel hub either is it?
 
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