Wonder why Some people have had lesser/milder

ticker_tape

Well-known member
Effects of the the C19.
They say with some people its barely noticeable.
I was tested at an early age I think 6 or 7 for TB, had the skin test and found to have immunity to it so I didn't need the jab at secondary school.
My mam said it was because she and my dad had TB as children.
 
I read somewhere that one of the reasons it has different effects is due to people's DNA. Also they believe blood groups are affected differently too. Blood Group A (which I am) being the worst.
 
Heard a doctor/scientist on the radio saying that early research from China is that smoking makes it worse.
 
It's just a facet of how diseases work. It's true of almost every disease you look at. Apart from certain strains of Ebola, with virtually every communicable disease more people have a mild form and recover from it, than die of it. In this specific aspect of things, it is similar to the flu. I've had the flu many, many times in my life but never had anything more than mild effects. Yet thousands of people die of the flu every year, often (like this virus) those with underlying conditions.

I think the more important question is why some people suffer the more serious effects and even die. As mentioned, underlying conditions are a major contributory factor but then there's the "cytokine storm" issue (which has also been cited as a possible reason for the high death toll in the 1918 H1N1 flu pandemic).

A cytokine storm is when the body's own immune system overreacts and in doing so, overwhelms the patient.
Sometimes the body’s response to infection can go into overdrive. For example, when SARS -CoV-2 – the virus behind the covid-19 pandemic – enters the lungs, it triggers an immune response, attracting immune cells to the region to attack the virus, resulting in localised inflammation. But in some patients, excessive or uncontrolled levels of cytokines are released which then activate more immune cells, resulting in hyperinflammation. This can seriously harm or even kill the patient.

Read more: https://www.newscientist.com/term/cytokine-storm/#ixzz6HZNI8cxA

As this article goes on to say:
Cytokine storms might explain why some people have a severe reaction to coronaviruses while others only experience mild symptoms. They could also be the reason why younger people are less affected, as their immune systems are less developed and so produce lower levels of inflammation-driving cytokines.
 
Reckon the amount of dosage you have can effect it as well. Quite a few f healthcare workers get it bad because they are treating multiple people so more virus gets in the body in the early stages making it more difficult for the body to fight it.

They reckon this is similar to other illnesses in households. It’s quite common for the first person not to be so bad but subsequent people get it worse
 
Yeah, what Gaz says, I've read/ heard that too. I read an article from some doctors and it's also what the nurses I know well are saying, so it seems this is the advice/ experience they're having too, so is likely legit.

The volume of the dose is expected to be a major factor, which they think is why loads of younger people and nurses are getting it. The younger getting it more as they're the ones out more, working, interacting, drinking in pubs etc, but it's the nurses I feel sorry for the most, having to deal with it.

Also the number that they "know" that have it, at out local hospitals is miles higher than the reported number, but nobody seems to be able to explain why.

The infected aren't even being put on wards which require the nurses to wear PPE (as they don't have enough), until they're confirmed as having the virus. So basically there's highly likely covid people in contact with none-covid nurses and doctors and non-covid other patients all the time, for the duration they go from not having test results, to having test results.

It's kind of an "everyone is well until proven sick" scenario, when medical staff think it should be "everyone is sick until proven well", but they don't even have the resources to do the latter if they wanted to.
 
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