Coronavirus good news thread

It would appear that the "dark data" that has been talked about actually is the T cell immunity that has protected far more of the population than the antibody tests show. Researchers at the Karolinska Institute in Sweden have data that confirms what I posted upthread.

Quote:
Study: Immunity to corona greater than antibody test shows
UPDATED YESTERDAY 23:16PUBLISHED YESTERDAY 23:08
People who have been tested negative for antibodies can still have so-called T-cell immunity against covid-19, according to a new report from Karolinska Institutet and Karolinska University Hospital.
- The results indicate that immunity to covid-19 is likely to be significantly greater in society than antibody tests have shown. If that is the case, then it is of course very good from a spread of infection, says Professor Hans-Gustaf Ljunggren at the Center for Infectious Medicine at KI.
T cells are one of the pillars of the immune system. They are white blood cells that help in the production of antibodies, and that also kill infected virus cells.
"Our results indicate that about twice as many people have developed T-cell immunity compared to those with which we can detect antibodies," says Marcus Buggert, associate professor at the Center for Infectious Medicine, KI, in a press release.
Unquote

In analysis of blood donor samples recently, 30% had covid T cells.

The vast majority of people are having mild or asymptomatic Sars Cov 2 infections because their innate immune system is taking care of the virus before it gets chance to take hold. The fact that a robust T cell defence against viral infections is helped by having adequate vitamin D levels also makes sense of why the elderly, BAME groups, the obese etc are most vulnerable (as they are most likely to have D deficiency.

Taken with the % that have antibodies, the % with T cell immunity would explain why the virus is finding it more difficult to find vulnerable hosts now. And, given recent weather, you'd expect fewer people to have vitamin D deficiency ... and to have a more robust immune system.

The full article is here. Should translate in Chrome.
https://www.svt.se/nyheter/inrikes/immunitet-mot-corona-storre-an-vad-antikroppstest-visar
 
It would appear that the "dark data" that has been talked about actually is the T cell immunity that has protected far more of the population than the antibody tests show. Researchers at the Karolinska Institute in Sweden have data that confirms what I posted upthread.

Quote:
Study: Immunity to corona greater than antibody test shows
UPDATED YESTERDAY 23:16PUBLISHED YESTERDAY 23:08
People who have been tested negative for antibodies can still have so-called T-cell immunity against covid-19, according to a new report from Karolinska Institutet and Karolinska University Hospital.
- The results indicate that immunity to covid-19 is likely to be significantly greater in society than antibody tests have shown. If that is the case, then it is of course very good from a spread of infection, says Professor Hans-Gustaf Ljunggren at the Center for Infectious Medicine at KI.
T cells are one of the pillars of the immune system. They are white blood cells that help in the production of antibodies, and that also kill infected virus cells.
"Our results indicate that about twice as many people have developed T-cell immunity compared to those with which we can detect antibodies," says Marcus Buggert, associate professor at the Center for Infectious Medicine, KI, in a press release.
Unquote

In analysis of blood donor samples recently, 30% had covid T cells.

The vast majority of people are having mild or asymptomatic Sars Cov 2 infections because their innate immune system is taking care of the virus before it gets chance to take hold. The fact that a robust T cell defence against viral infections is helped by having adequate vitamin D levels also makes sense of why the elderly, BAME groups, the obese etc are most vulnerable (as they are most likely to have D deficiency.

Taken with the % that have antibodies, the % with T cell immunity would explain why the virus is finding it more difficult to find vulnerable hosts now. And, given recent weather, you'd expect fewer people to have vitamin D deficiency ... and to have a more robust immune system.

The full article is here. Should translate in Chrome.
https://www.svt.se/nyheter/inrikes/immunitet-mot-corona-storre-an-vad-antikroppstest-visar
No evidence that vitamin D helps with coronavirus
 

There are plenty of studies that suggest otherwise and, given the well established role of Vitamin D in our immune response to viral and bacterial infection and its established role in mediating inflammatory response, I'm confident that it will emerge as playing a key role. I haven't the link to hand but there was BMJ post within the last few days stating that saying that Vitamin D played no role in Covid severity is plain wrong.

Anyway, it'll come out in the end.

Here's more on the T cell immunity I posted about yesterday.

https://medicalxpress.com/news/2020-06-immunity-covid-higher-shown.html
 
There are plenty of studies that suggest otherwise and, given the well established role of Vitamin D in our immune response to viral and bacterial infection and its established role in mediating inflammatory response, I'm confident that it will emerge as playing a key role. I haven't the link to hand but there was BMJ post within the last few days stating that saying that Vitamin D played no role in Covid severity is plain wrong.

Anyway, it'll come out in the end.

Here's more on the T cell immunity I posted about yesterday.

https://medicalxpress.com/news/2020-06-immunity-covid-higher-shown.html
When it's peer reviewed it will probably be included. They have only analysed peer reviewed published reports.

The link I put up concluded the value of supplementary Vitamin D, but not as a means of Covid-19 prevention.

I linked the BMJ response before.
 
The difficulty in proving something is effective is regression to the mean. Supplementing Vit D if you have healthy levels will be unlikely to improve anything. If you are deficient then it will always be beneficial as it is a fundamental vitamin.

In retrospective studies it is easy to link a to b, especially in health profile- e.g older people and vit D deficiency- however often these studies don't identify the low vit D population who never entered the research setting/ hospital.

I do wonder in the elderly and more vulnerable whether we should supplement appropriately across the board to maximise their health profile- although that would take funding/ support.
 
There's no point in supplements for those with adequate levels, but it would seem sensible to try to boos the levels of those people who are deficient ... for all kinds of reasons. The elderly don't get out much and tend to have low vit D levels, plus their T cell response is weaker .... it's strongest in young people. BAME medics on the frontline are already supplementing as a precaution. Most people are deficient in late winter ... but have decent levels until the autumn (as it is stored in fat for a time).
 
I started taking it in April. My line of work means some days, especially in the winter months I won't see natural daylight for any sort of length of time. Some days I won't see it at all, if I'm doing s breakfast shift for example.

This report saying vitamin D does nothing to protect against covid-19 is a very dangerous report to release as surely any sort of extra vitamin intake is better than none at all.
 
I started taking it in April. My line of work means some days, especially in the winter months I won't see natural daylight for any sort of length of time. Some days I won't see it at all, if I'm doing s breakfast shift for example.

This report saying vitamin D does nothing to protect against covid-19 is a very dangerous report to release as surely any sort of extra vitamin intake is better than none at all.
The report says exactly that. Keep taking it.
 
Remdesivir stock for U.K. confirmed (feels a bit ‘dirty’ calling this good news when many countries are probably going to lose out following US aggressive purchasing) and a hint further ongoing tests may be about to yield some positive results ? 🤞🏻?🤞🏻🤞🏻


‘Dr Hill said some results of the drug studies will be announced at an international conference next week, adding: "I can't tell you anything right now. But it's definitely time to watch this space and think about alternatives too."
 
Remdesivir stock for U.K. confirmed (feels a bit ‘dirty’ calling this good news when many countries are probably going to lose out following US aggressive purchasing) and a hint further ongoing tests may be about to yield some positive results ? 🤞🏻?🤞🏻🤞🏻


‘Dr Hill said some results of the drug studies will be announced at an international conference next week, adding: "I can't tell you anything right now. But it's definitely time to watch this space and think about alternatives too."
There must be an absolute concrete reason as to why Trump's administration bought up all that stock.
Oh to be a fly on the wall behind closed doors.
 
I think there are due to be several publications announced at a COVID symposium next week. It may be that this has something to do with it. I'm just speculating from other things I have read.
 
I think there are due to be several publications announced at a COVID symposium next week. It may be that this has something to do with it. I'm just speculating from other things I have read.

Do you mean in the sense of further evidence to suggest Remdesivir is a good treatment?
Or that nothing else successful found YET, (other than dexamethasone) so the US have bought up Remdesivir out of panic, for want of a better term?
 
Do you mean in the sense of further evidence to suggest Remdesivir is a good treatment?
Or that nothing else successful found YET, (other than dexamethasone) so the US have bought up Remdesivir out of panic, for want of a better term?

I'm not entirely sure- not looked into it further. I'm speculating. Will look back and work out who is presenting and what they are working on- might be able to clarify.
 
At least there is a plentiful alternative treatment that costs 1/100 of the price and is being generally used by the NHS.
But 170+ people are dying everyday, no stats to show who has recovered from the virus in hospitals so is it actually making a difference?
 
But 170+ people are dying everyday, no stats to show who has recovered from the virus in hospitals so is ott actually making a difference?
Dexamethasone had a limited success rate in saving lives (15-20%), whereas the Remdesivir studies showed it didn't save lives but reduced time in ICU. Hospital deaths are falling.
 
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